She presented to the hospital emergency center, reporting nasal congestion and sneezing of 5 days duration pulsatile headache in the left hemicranium 3 days prior to admission, with intensity 6/10 according to the visual analogue scale, accompanied by phosphenes, photophobia and diplopia with subsequent developing right hemiparesis over a 26-hour period who delayed seeking emergency care for fear of COVID-19. This case report follows the CARE Guidelines 16.ģ7-year-old woman, environmental health technician with a history of rheumatic fever during childhood, hypertension and smoking for 2 years denies traumatic events and use of oral contraceptives. We report a case of a 37-year-old female patient with a positive PCR-RT swab for COVID-19, with a neurological manifestation as a result of internal carotid artery occlusion. With inflammation, prothrombotic coagulopathy and endothelial injury as mechanisms involved 15.Īcute viral infections, oxidative stress, hypoxia, and turbulent blood flow have been established to act as triggers that increase the short-term risk of ischemic stroke and other arterial thrombotic events, such as myocardial infarction 15. They are particularly prone to expel their contents, with antimicrobial agents stored in their granules, a process known as neutrophil extracellular trap formation (NET) 10, 11.Įxcessive NET formation leads to the formation of aggregates 12 that occlude vessels 13 and ducts 14, causing damage to tissues. These cells are also found in immune-mediated inflammatory diseases 9. Activated neutrophils that fail to extravasculate are partially degranulated in the circulation 8 which, due to their low floating densities, are known as low-density granulocytes. Neutrophil activation is an important clinical feature in COVID-19 being the first to respond to the invasion of pathogens and tissue damage that mediate the death of pathogens by oxidative explosion and phagocytosis 7. Recent publications from China, France and New York raise the possibility that COVID-19 may increase the risk of ischemic stroke 5, 6. COVID-19 has affected more than 39.2 million people and caused more than 1,100,000 deaths worldwide 2 and although it is primarily a respiratory disease, scientific studies suggest that it can lead to a hypercoagulable state and thrombotic complications 3, 4. COVID-19 is a new disease caused by the SARS-CoV-2 virus (Severe Acute Respiratory Syndrome Coronavirus 2) that is spreading rapidly around the world 1.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |